Metabolic alterations associated with T2D are well characterised by epidemiological and research based experiments. The pathogenesis and progression of T2D is ascribed to 4 mechanisms; amplified advanced glycation stop item (AGE) development, improved polyol pathway flux, activation of protein kinase C (PKC) isoforms, and enhanced hexosamine pathway flux[seven]. Until recently https://www.directivepublications.org/journal-of-diabetology-research/