Substitution at R3 with a halogen or alkoxy group (74f–74i) triggered a slight rise in cellular potency Along with the halide analogs (74g–h) exhibiting maximum the potency while in the group. More optimization led to the discovery of 74i–j, with 74k as one of the most active compound in the https://indazoleproducts19752.timeblog.net/67321560/what-does-indazole-structure-mean