Epidural clonidine employed being an adjunct to regional anesthetics has 3 distinct mechanisms of action. First, the stimulation of alpha-two-receptors within the dorsal horn reduces pain transmission. Secondly, clonidine could potentially cause neighborhood vasoconstriction that restrictions vascular removal of regional epidural anesthetics. One of several theories regarding the mech... https://whatischronicpain54209.ziblogs.com/32180214/the-basic-principles-of-onolidine